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Roderick
MacKinnon: award-winning neurobiologist
An
award-winning scientist, Dr. Roderick MacKinnon has produced groundbreaking
research detailing the way the body's electrical systems function,
by unlocking the secrets of the body's ion channel proteins.
Before
MacKinnon came along, medical science knew that ion channels were
important but not much else; the channel's architecture and precise
operation remained a mystery. But in 1998, MacKinnon unlocked
the channel's secrets, resulting in one of the biggest scientific
breakthroughs of the year.
The
discovery may lead to the creation of pharmaceuticals that are
more targeted and more effective. Described by Science Magazine
as "one of the 10 biggest science stories of 1998," MacKinnon's
work earned him one of science's top honors.
In
1999, he was awarded the Albert Lasker Basic Medical research
Award -- the nation's most distinguished honor for outstanding
contributions to basic and clinical medical research. The prizes
were established in 1946 and are often called "America's Nobels"
-- more than half of all Lasker winners since 1962 have gone on
to win the Nobel Prize.
A
professor of Molecular Neurobiology and Biophysics at the Rockefeller
University and an investigator with Howard Hughes Medical Institute,
MacKinnon was elected to the U.S. National Academy of Sciences
in 2000.
He
received a bachelor's degree in biochemistry from Brandeis University
and a medical degree from Tufts University School of Medicine.
He completed his residency in internal medicine at Beth Israel
Hospital and postdoctoral work at Brandeis with Christopher Miller.
Dr.
MacKinnon has received numerous awards for his research, including
the 2000 Rosenstiel Award and the 2001 Gairdner Foundation International
Award.
He
is a member of the Alpha Omega Medical Honor Society, a PEW scholar
in the BioMedical Sciences and the recipient of the McKnight Scholars
Award, the Biophysical Society Young Investigator Award, the McKnight
Investigator Award, the W. Alden Spencer Award and the AAAS Newcomb
Cleveland Prize.

Information
for this biography provided by Tufts Medicine and Rockefeller
University.
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